Lupoid cutaneous leishmaniasis in Afghanistan treated with 0.045% DAC N-055
نویسندگان
چکیده
Introduction / objectives Lupoid leishmaniasis (LCL) is a rare, face disfiguring, treatment resistant complication which has responded to the expensive photodynamic therapy in 5 patients in Iran [ F. Ghaffarifar et al. La Rev. de la Méditerranée orientale Vol. 12 No. 6, 2006]. Here we report 5 cases,photodocumented as best as we could under the actually disastrous conditions of Afghan Health Care,treated with 0.045% DAC N-055 [German Drug Codex, 1990], which is split into O2 and 2NaClO2 after 360 nm light exposure and reacts as chlorite in iodometry.
منابع مشابه
A randomized controlled phase IIb wound healing trial of cutaneous leishmaniasis ulcers with 0.045% pharmaceutical chlorite (DAC N-055) with and without bipolar high frequency electro-cauterization versus intralesional antimony in Afghanistan
BACKGROUND A previously published proof of principle phase IIa trial with 113 patients from Kabul showed that bipolar high-frequency (HF) electro-cauterization (EC) of cutaneous leishmaniasis (CL) ulcers and subsequent moist wound treatment (MWT) closed 85% of all Leishmania (L.) tropica lesions within 60 days. METHODS A three-armed phase IIb, randomized and controlled clinical trial was perf...
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